Details: KO 9.30 pm ET, Fox Sports 1
Live stream info: How to watch Copa America live online.
United States are massive underdogs in Group A behind Colombia, Costa Rica and Paraguay. But with an enormous home support behind them and the team riding on momentum, US are hoping to progress beyond the group stages.
The hosts are currently riding on confidence following three straight victories in warm up games against Puerto Rico, Ecuador and Bolivia. But, we all know, these results hardly mean anything.
US manager Jurgen Klinsmann believes his team is capable of beating Colombia on the opening match.