Tottenham are on their worst run in the FA Cup since 1978 when they broke a six-year run of failing to move past the fourth round.
Since 2012, they've fallen to Leeds United, Arsenal and Leicester City in the early stages.
Having drawn League One strugglers Colchester United in this year's competition, they'll be hoping to improve on that record.
Colchester are rock bottom, 24th, in League One. They've won just eight games this season, but three of those have come in the FA Cup.
None of their vanquished foes so far—Wealdstone, Altrincham and Charlton—are on Spurs' level, but their ability to rise in the cup should be noted.