Both teams will be desperate to get one over their rival and it will be a fascinating contest.
Celtic have had a poor start to the season by their standards and the fans will be expecting a big reaction here.
Meanwhile, Rangers have been unbeatable under the management of Steven Gerrard. Although they have drawn a fair few, they will fancy their chances here.
Celtic have enjoyed a great head-to-head record against the Gers over the last few seasons but on current form, that streak could come to an end later today.