Michaell Chirinos scored in the second half as Lobos BUAP beat Chivas Guadalajara 1-0 at the Estadio Akron to add further misery to the Rojiblancos.
The defeat means Chivas are five points away from eighth place Puebla with only four games left to play in the regular season.
Chivas, who arrived to this match on the back of two straight Liga MX defeats, started on the front foot. Alexis Vega created the first big opportunity of the game when he sent a shot just inches wide of the Puebla goal.
Vega would eventually put his name on the stat sheet but not for a good reason.