The UEFA Nations League starts in September, with 55 teams competing in four leagues in the newly-formed competition.
Highlights of the opening round of games include England’s clash with Spain on Saturday, while World Cup winners France visit Germany two days earlier.
Spain will be amongst the favourites to win the competition at the new sportsbook from FanDuel, although England will fancy their chances of success when the two sides meet at Wembley.
Manchester City star Raheem Sterling and Liverpool forward Adam Lallana have withdrawn from the squad through injury, but the Three Lions are still expected to field a strong team.