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Last season's finalists Tottenham Hotspur face a tough task to qualify for the quarter-finals of the UEFA Champions League, as they head to RB Leipzig trailing 1-0 from the first leg in north London.
Jose Mourinho's side are also without injured forwards Harry Kane, Heung-Min Son and Steven Bergwijn and face a home team on a run of seven games without defeat.
Elsewhere, Atalanta will be expected to continue their memorable debut in Europe's elite competition by knocking La Liga side Valencia out of the competition.
Gian Piero Gasperini's team take a 4-1 lead to Mestalla for the game which will be played behind closed doors in an effort to contain the spread of coronavirus.