Manchester United welcome back former hero Cristiano Ronaldo in the UEFA Champions League on Tuesday, as Juventus head to Old Trafford in Group H.
Elsewhere Barcelona must make do without the injured Lionel Messi against Inter Milan at the Camp Nou. The captain has been their inspiration with five goals in their first two wins, but he'll be on the sidelines after fracturing a bone in his right arm against Sevilla on Saturday.
There are plenty of other tasty ties around Europe to look forward to. Borussia Dortmund host Atletico Madrid, Paris Saint-Germain take on Napoli, while Premier League champions Manchester City are away at Shakhtar Donetsk.