Roma visits Bayer Leverkusen looking for a first Champions League win of the season in what Daniele De Rossi terms a "mini knockout game."
Daniele De Rossi knows Roma can ill-afford another defeat when it takes on Bayer Leverkusen if it is to keep its Champions League hopes alive.
Roma travels to Germany for Tuesday's encounter sitting bottom of Group E with just one point from its opening two matches.
An encouraging 1-1 home draw with defending champion Barcelona on matchday one was followed by a shock 3-2 defeat at BATE, in which Rudi Garcia's men found themselves three goals down within half an hour.