Atletico Madrid will be aiming to secure second place when they welcome Real Valladolid to the Wanda Metropolitano on Saturday afternoon.
Atleti may mathematically still be in contention for the title, but it would take a slip up of extraordinary proportions for Barcelona not to be crowned champions at this stage.
However, Diego Simeone will be expecting his team to continue fighting, and to show the sort of flair and creativity that saw them put three past an obstinate Valencia side on Thursday night.
Real Valladolid by comparison have absolutely everything to play for.