Atletico Madrid tumbled to a 2-1 home defeat by Benfica at the Vicente Calderon.
Nicolas Gaitan and Goncalo Guedes were the goalscorers, after Angel Correa had put Atletico in front.
It was a surprise result, because Diego Simeone's side are notoriously good at home in Europe, and it puts the Portuguese outfit in command of Group C, with six points to Atletico's three, while Galatasaray and Astana have one each.
Here are the winners and losers from the game...