The defender sustained the injury during France Under-21's clash with Scotland on Thursday and is set to be out for a prolonged period after scans confirmed the problem.
Aymeric Laporte is set for a lengthy spell on the sidelines after Athletic Bilbao confirmed that he suffered a broken leg and dislocated ankle while on international duty.
Highly-rated defender Laporte, a transfer target for incoming Manchester City boss Pep Guardiola, sustained the injury to his right leg in a tackle while playing for France Under-21s against Scotland on Thursday.
The 21-year-old was carried off on a stretcher and, following scans, Athletic announced the severity of his injury on Friday.