Arsenal's defensive problems have gone from bad to worse for manager Unai Emery after Ainsley Maitland-Niles picked up a knock in the 5-1 defeat to Liverpool on Saturday.
The Gunners' utility man filled in on the wing at Anfield and is now down as a doubt for Tuesday's London derby clash with relegation threatened Fulham.
Konstantinos Mavropanos and Rob Holding will definitely be absent on Tuesday, with Nacho Monreal and Hector Bellerin both doubts, and options at the back are becoming scarce during a busy run of games.
With the defence becoming so depleted by injury, Emery's hand may be forced in the January transfer window.