Tottenham Hotspur will look to tighten their grip on second against Europa League-chasing Southampton, before Manchester City host Arsenal with a place in the Champions League at stake. Liverpool also take on Watford.
Meanwhile, it's the penultimate day of the season in La Liga, with Barcelona, Atletico Madrid and Real Madrid all battling for top spot.
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7': GOAL FOR CITY! Aguero scores! Fernandinho knocks down the ball inside the box and Aguero slots home with his left foot in the bottom corner!