The inability to beat Alabama was a large part of Les Miles' demise in Baton Rouge. If Ed Orgeron is able to upend the No. 1 Crimson Tide, it will go a long way toward giving him the full-time job. Are the Tigers up to the task?
Also, visit our college football PickCenter page for additional information on these games and many more.
Let's get on with the Week 10 game picks:
No. 1 Alabama at No. 13 LSU
8 p.m. ET, CBS
No. 11 Florida at Arkansas
3:30 p.