The Alabama Crimson Tide own a significant lead in the rivalry with the Ole Miss Rebels, winning 49 of 60 meetings all-time. But the Rebels have won two of the last three meetings, and they're 7-3 against the spread over the last 10. The Rebels challenge the top-ranked Crimson Tide on Saturday night in Tuscaloosa.
College football point spread: The Crimson Tide opened as 28-point favorites, according to sportsbooks monitored by OddsShark (line updates and matchup report).
College football betting pick, via OddsShark computer: 50.3-15.7 Crimson Tide (college football picks on every game).