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Missouri Tigers vs. Alabama Crimson Tide Odds, College Football Betting Pick

Alabama is rolling toward another College Football Playoff berth, but with that total dominance comes huge point spreads. And unfortunately for their financial backers the Crimson Tide are 0-3 against the spread the last three weeks. Alabama faces another big line for Saturday night's match with Missouri in Tuscaloosa.

College football point spread: The Crimson Tide opened as 28-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)

College football betting pick, via OddsShark computer: 52.6-26.2 Crimson Tide (College football picks on every game)

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