In trying to contain the NFL’s number one offense over the first four weeks, the Seattle Seahawks defense will need to overcome the loss of one of their most reliable starters since the 2013 season. Defensive end Cliff Avril has been ruled out for the game with a neck injury that he suffered in Week 4’s win over the Indianapolis Colts. It’s impossible to say when he will return, but the Seahawks do have a Bye in Week 6.
Seattle may also be without starting cornerback Jeremy Lane, who is doubtful with an ankle injury.