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Pro Picks: Are Bills ready to grab AFC East from Patriots?

Not since the pre-Tom Brady days have the Bills been such a factor in the AFC East. A victory Saturday at New England would lift Buffalo into a tie atop the division the Patriots have ruled for the last decade.

This is an opportunity for the Bills to stamp themselves as title contenders — not just division championship but Super Bowl threats. Gillette Stadium is about the most unkind place in the NFL for the Bills, and Brady has made a living beating them.

So, do things change when Buffalo (10-4) heads to New England (11-3)? Are the Bills ready for such a challenge?