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‘Monday Night Football’ preview, predictions, and open thread: 49ers at Cardinals

The Arizona Cardinals (+13.5)

and San Francisco 49ers (-13.5) head to Mexico City to face each other on Monday Night Football this week. Despite coming off of a 27-17 win over the division rival Los Angeles Rams (+14.5), the Cardinals are a team that is sputtering. They have lost 3 of their last 5 games with their only wins coming against teams quarterbacked by Andy Dalton and John Wolford. The 49ers have also lost 3 of their last 5 games, however they have looked like a very different team over their last two games, both of which were wins, thanks in large part to the addition of Christian McCaffrey.