Kyle Seager and Cano each hit solo homers off Dallas Keuchel in the first three innings, and Mariners right-hander Nathan Karns turned a 2-1 lead over to his bullpen after allowing one run and six hits with nine strikeouts in 6 1/3 innings..
The no-decision leaves Karns at 3-1 with a 3.38 ERA. Cano went 4-for-5 and Seager was 3-for-4, adding a triple in the eighth. Mariners relievers Nick Vincent and Joel Peralta each stranded runners in scoring position in the seventh and eighth innings. Cishek couldn't close the door as he took his first blown save in 10 chances, but he came back to pitch a scoreless 10th and earn the win.