Trailing 5-4 in the final moments, Joonas Donskoi scored with 15.8 seconds remaining and the Sharks scored in OT to pull out the win over Arizona.
Marc-Eduoard Vlasic's goal at 2:42 in overtime served as the game-winner. It was challenged by the Coyotes, but allowed about review by the Situation Room.
Donskoi's game-tying goal was his second of the night. Joe Thornton, Joe Pavelski and Logan Couture also scored in the first period.
Martin Jones got the start, but after allowing three goals in the first period, he was pulled for Aaron Dell.