Span received immediate attention from the Giants' athletic training staff in the dugout and his departure became official when Conor Gillaspie pinch-hit for him in the third inning.
Gorkys Hernandez, who started in right field for San Francisco, moved to center field while Eduardo Nunez, the Giants' everyday third baseman, shifted to right, his first appearance in the outfield since 2015 with the Twins. Regular right fielder Hunter Pence, who bruised his left knee while losing Blackmon's line drive in the lights for an inside-the-park homer Friday, remained on the bench.