San Francisco finished the game 0-for-7 with runners in scoring position, including a couple of critical missed chances in the seventh.
"We just couldn't generate any offense," Giants manager Bruce Bochy said. "We just couldn't get much going."
On the season, San Francisco has been more than capable with runners in opportune spots. Entering Thursday's game, the club had a .286 batting average with runners in scoring position -- the best mark in the National League West.
But the last few games haven't reflected that potency. In their three-game series with the Cardinals, the Giants were 3-for-26 with runners in scoring position.