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Yet another 49ers running back is expected to miss time with an injury

Yet another San Francisco 49ers running back seems set to miss some action, as ESPN insider Adam Schefter reports “it looks as if” Isaac Guerendo will miss Sunday’s matchup against the Miami Dolphins with a hamstring injury.

The rookie missed Wednesday’s practice with the same injury, which head coach Kyle Shanahan said occurred during last Thursday’s loss to the Rams. It’s a bit unclear when exactly the Niners found out about the injury, as Shanahan didn’t reveal it in a day-after-game conference call with reporters Friday, but clearly it’s looking bad enough for an insider to say Guerendo is “unlikely to play” a day before the official injury report.