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What’s your biggest concern about the 49ers?

Welcome to SB Nation Reacts, a survey of fans across the NFL. Throughout the year, we ask questions of the most plugged-in San Francisco 49ers fans and fans across the country. Sign up here to participate in the weekly emailed surveys.

Thursday feels like a must-win game for the 49ers. The team can ill-afford to fall to 0-3 in the NFC West and has yet to defeat an NFC team in 2024. Sunday’s loss to Arizona was brutal, and there was plenty of blame to go around for the 49ers.