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The San Francisco 49ers travel to face the Arizona Cardinals in Week 4. Find information here on the 49ers-Cardinals game time, TV channel, live online streaming options, radio, announcers and more!

Welcome back for another week of San Francisco 49ers football! The 49ers travel to Glendale to face the Arizona Cardinals. The game time is 1:05 p.m. PT, and will air on FOX. The announcers in the booth will be Sam Rosen and David Diehl, and the sideline reporter will be Jen Hale. The 49ers are a 6.5-point underdog, according to our friends at Odds Shark.

The 49ers head into this game sitting at 0-3, and bringing up the rear in the NFC West. After a bad Week 1 loss at home to the Carolina Panthers, the 49ers lost at home to the Seattle Seahawks and on the road to the Los Angeles Rams by a combined five points.