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The 49ers and Cardinals defenses are headed in opposite directions

Following a dominant performance by the San Francisco 49ers' defensive line against the Patriots, Kyler Murray and the Cardinals present a different set of problems for the 49ers at all defensive levels. The goal is to contain Murray in the pocket, but the run game with Murray and James Conner will cause conflict and test the 49ers’ discipline.

Arizona's defensive line is injured, and its secondary has been routinely torched. Let’s examine all three defensive groups for Arizona and San Francisco.

Defensive Line

RE L.J. Collier - 5 pressures, two QB hits, three hurries, 5.