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Should I take the 49ers +8.5 vs. Rams?

Every Wednesday evening, a proxy service sends out the full list of odds for the weekly NFL action. I have to pick five games for the Westgate SuperContest, based on the lines emailed out Wednesday evening. If I want to pick Thursday Night Football, I have to get all five picks in by 9 a.m. PT on Thursday. If I do not include TNF, I have until 7 p.m. PT on Friday. The lines do not change once they are emailed out on Wednesday.

Normally I try and avoid the San Francisco 49ers in my picks. I feel like I am a little too close to them, and thus emotion might impact my pick.