INDIANAPOLIS - A pair of rookie draft picks, cornerback Ahkello Witherspoon and linebacker Pita Taumoepenu, will make their NFL debuts today for the 49ers against the Colts at Lucas Oil Stadium.
Witherspoon, a third-round pick, and Taumoepenu, a sixth-round pick, are active because defensive back Adrian Colbert (hamstring) and linebacker Dekoda Watson (groin) are sidelined. Linebacker Reuben Foster (ankle) and safety Eric Reid (knee) are also out.
The 49ers’ other inactives are center/guard Erik Magnuson, wide receiver Kendrick Bourne and linebacker Mark Nzeocha.
On Thursday, defensive coordinator Robert Saleh was asked about the progress of Witherspoon, the No.