The San Francisco 49ers are coming off a brutal loss against the Los Angeles Rams and get a step down in competition against the Arizona Cardinals. This would seem great if it wasn’t for the fact the 49ers lost to the Cardinals just two weeks prior in Santa Clara. The team has not won a game since Week 2 and the Cardinals’ only win of the season came against the 49ers. For draft positioning, a loss would be nice but most would like to see some better things from the 2018 49ers instead of bad defense and turnovers. This will be an afternoon game kicking off at 1:25 PM.