A statistical look at the 49ers’ 45-16 loss to the Buffalo Bills on Sunday in Orchard Park, N.Y.:
1: Touchdown pass for 49ers’ quarterback Colin Kaepernick in his first start of the season. It was his first TD pass since Oct. 18, 2015.
3: Points scored by the 49ers in the second half. They trailed just 17-13 at the break.
3: Rushing touchdowns for Buffalo Bills running back LeSean McCoy.
4: Consecutive wins for the Bills, the first time Buffalo has done that since 2008.