are on the road against the 4-6-1 Indianapolis Colts (+1.5). Mike Tomlin and Kenny Pickett against Jeff Saturday and Matt Ryan. Of course, there are far more reasons to pick a side.
Tomlin is one of the best coaches of all time as an underdog. Pittsburgh is a 2.5-point underdog at DraftKings with a total of 39.5. The Steelers' offense has woken up during the past few weeks, while the Colts have trended in the opposite direction.
Both of these teams are solid defensively. The Steelers are 14th in DVOA, while the Colts are in DVOA.