An injury-riddled season for the San Francisco 49ers has hit hardest in the backfield, with both Christian McCaffrey and Jordan Mason now on injured reserve and possibly done for the season. So how do the Niners expect to replace their two injured lead backs? A heavy dose of Isaac Guerendo, according to ESPN insider Jeremy Fowler in a Saturday notes column.
"RB Isaac Guerendo is prepared to carry a heavy workload for San Francisco over the final five games,” Fowler wrote. “This could lead to something promising. He’s 220 pounds and runs a 4.