The San Francisco 49ers have faced their fair share of injuries this season, with a number of starters missing multiple weeks, which has been a part of their early-season struggles.
Offensively, San Francisco has missed running back Christian McCaffrey for the entire season, while they recently lost wide receiver Brandon Aiyuk for the year after he suffered a torn ACL and MCL this past weekend.
Defensively, the 49ers have seen a number of issues crop up as well, as defensive tackle Javon Hargrave will likely miss the rest of the year with a triceps injury, while safety Talanoa Hufanga has been in and out of the lineup with a variety of issues.