The San Francisco 49ers are picking at No. 2 in the first round of the NFL Draft. Unlike last year, when the team picked ninth overall, there won’t be much of a wait for the 2019 selection. The draft starts at 5 p.m. PT. Each team gets 10 minutes to select a player. So if you are running late from work, or if you are cutting it close in general, you have a little bit of leeway. Barring a trade, and assuming the Arizona Cardinals take the entire time they are allotted, the 49ers will pick at 5:10 p.