Well-rested 49ers might be meeting Eagles at just the right time (paywall)
“The 49ers will likely meet the Eagles with just one season-opening starter unavailable. Safety Talanoa Hufanga was placed on injured reserve last week with a torn ACL.
As for the Eagles, All-Pro right tackle Lane Johnson didn’t play against the Bills due to a groin injury that developed late in the week and All-Pro defensive tackle Fletcher Cox (groin) and linebacker Zach Cunningham (hamstring), their second-leading tackler, didn’t finish the game. Eagles tight end Dallas Goedert is on IR with a forearm injury.