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49ers RBs Christian McCaffrey, Jordan Mason both headed to IR

“After McCaffrey departed, Mason capably filled in, much like he has all season. Mason had 13 carries for 78 yards against Buffalo, despite the ankle injury and, at one point, being evaluated and cleared for a concussion.

Mason finishes his season while leading the Niners in rushing with 789 yards and three touchdowns through the team’s first 12 games. McCaffrey posted 202 rushing yards and no touchdowns in his abbreviated action. Mason is set to be a restricted free agent after the season with McCaffrey under contract at a cap charge of $9.