A road matchup against the Arizona Cardinals awaits the San Francisco 49ers in Week 3 of the NFL season. The 49ers will look to bounce back from last week’s loss to the Pittsburgh Steelers and get a big win in their first of six NFC West contests. Arizona enters the game as one of the league’s nine remaining unbeaten teams following back-to-back wins against the New Orleans Saints and Chicago Bears. San Francisco holds a 29-18 overall advantage in the all-time series against Arizona and have won 10 of the last 12 meetings between the two clubs.
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