We may only be in the third week of the NFL season but, in the context of the quickly changing NFC, the San Francisco 49ers game at the Arizona Cardinals has the feel of a matchup that will be crucial in determining the playoff picture at the end of the campaign.
San Francisco has a good record against the Cardinals in recent years. Indeed, quarterback Colin Kaepernick is 4-1 versus Arizona as a starter, however, that record may be tough to maintain this Sunday.
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Bruce Arians’ Cardinals are 2-0 following comfortable wins over the New Orleans Saints and the Chicago Bears, with a healthy Carson Palmer throwing for 492 yards and seven touchdowns in the opening two games.