The San Francisco 49ers travel to the southwest to face the Arizona Cardinals in Week 10 at 1:05 p.m. PT. This week features some notable bye weeks, with the Indianapolis Colts, Buffalo Bills, Detroit Lions, and Oakland Raiders on bye. We have been dealing with six-team bye weeks the past couple weeks, so this is an improvement, but a lot of notable talent will be sidelined.
The 49ers and Cardinals squared off earlier this season, and a game that started out looking like there was a decent shot of a scoreless tie turned into a shootout. The Cardinals took advantage of 49ers miscues to get their own offense going, while the 49ers got some significant garbage time numbers.