The San Francisco 49ers begin divisional play with a Week 3 road matchup against the unbeaten Arizona Cardinals.
San Francisco has won 10 out of the last 12 meetings, including the most recent in Week 17 of last season when the 49ers won at home, 20-17.
The 49ers will be looking to bounce back from their first loss of the year, a 43-18 defeat at the hands of the Pittsburgh Steelers.
Here are the experts' picks from around the web for the Week 3 clash. Give us your predictions in the comment section below...
Pete Prisco of CBS Sports: Cardinals 27, 49ers 17
"The 49ers will be playing consecutive road games in this one.