After giving up a touchdown on the opening drive of the game, the San Francisco 49ers starting defense responded with two goal-line stands against the Houston Texans.
The Texans had 1st-and-goal from the 49ers 1-yard line with 4:10 remaining in the opening quarter. San Francisco stopped Houston running backs Jay Prosch and Alfred Blue on first and second down respectively. A pass interference on third down gave Houston a fresh set of downs, again from the 1-yard line. Houston fullback Kenny Hilliard was stopped twice at the goal line, running back Joseph Grimes was stopped once and Blue was stuffed again on fourth down.