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49ers vs. Cardinals predictions: Will the Niners end the losing streak?

The San Francisco 49ers are officially playing out the string after being eliminated from playoff contention following their Week 15 loss to the Dallas Cowboys. The Niners will play the penultimate game of their 2020 regular season against the Arizona Cardinals.

Nick Mullens suffered an elbow injury against the Cowboys, meaning C.J. Beathard will start at quarterback for the first time since 2018. The 2017 third-round pick is 1-9 in his last 10 starts and will have the recently-signed Josh Rosen backing him up.

Tight end George Kittle is expected to return to the lineup, which will give a big boost to the struggling Niners’ offense.