On Monday Night Football, the San Francisco 49ers will play their first game of the season without Ahkello Witherspoon, who couldn’t have started the season any better. It’ll be the team’s second game without star left tackle, Joe Staley, as well. The bye week and a couple of extra practices to start this week should help with preparation. That doesn’t mean Justin Skule and Emmanuel Moseley will be ready for everything the Cleveland Browns throw at them.
If I’m the Browns, it’s simple. I isolate my best player against your “new guy” early and often to test them.