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49ers-Seahawks: Adrian Colbert ruled out, Trent Brown hurt shoulder in practice

San Francisco 49ers head coach Kyle Shanahan delivered some bad news on Friday, confirming that rookie safety Adrian Colbert will not be active against the Seattle Seahawks as he is not sufficiently recovered from surgery on his broken thumb. In addition to that, the 49ers have a new injury to one of their best players as right tackle Trent Brown is dealing with a shoulder issue.

The 49ers will be down to their fourth starting free safety on Sunday, probably veteran Antone Exum, though Dexter McCoil is also in the discussion.