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49ers S Talanoa Hufanga is questionable for Sunday after rolling his ankle at practice

The San Francisco 49ers saw Deebo Samuel, George Kittle, Dee Winters, Jacob Cowing, and Jordan Elliott all practice on Friday. General manager John Lynch said it would be a big day for Deebo to determine whether he’d play in Week 4 against the New England Patriots.

Kyle Shanahan gave the final injury report after Friday’s practice:

QUESTIONABLE

WR Deebo Samuel (calf strain)

LB Dee Winters (ankle)

DT Jordan Elliott (foot)

S Talanoa Hufanga (ankle)

LT Trent Williams (toe sore)

Williams missed Wednesday’s session with an illness, but came in this morning with some soreness in his toe after, “it acted up a little bit in practice yesterday.