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49ers-Rams Week 3 odds: Niners open as 7.5-point road favorites

The San Francisco 49ers saw their first loss of the season in Week 3, as they dropped a 23-17 road contest to the Minnesota Vikings in Week 2, falling to 1-1 on the year.

After a dominant start to the year, San Francisco saw mistakes compound in Week 2, as turnovers, sacks, and execution issues led to a rough outing against a well-coached Vikings team.

Now, looking ahead to Week 3, the 49ers will go on the road for a matchup with their division rival, the Los Angeles Rams, who are coming off a brutal 41-10 beatdown by the Arizona Cardinals in Week 2.