Week 1
Sept. 12 vs. Los Angeles Rams (7:20 p.m., ESPN)The Chip Kelly era opens in prime time against the reborn Los Angeles Rams, who drafted Cal quarterback Jared Goff No. 1 overall. A home win over the Rams in last season's finale (19-16, overtime) kept the 49ers from going 0-6 in the NFC West.Week 2Sept. 18 at Carolina Panthers (10 a.m. PT, Fox)Last time in Charlotte, on Jan. 12, 2014, the 49ers took a 23-10 divisional-round victory as Colin Kaepernick passed for a touchdown and ran for one. The Panthers have a few extra days of rest after opening in the NFL Kickoff game (and Super Bowl 50 rematch) at Denver.