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49ers must be sure to stop these 3 Lions stars on Sunday

Running back D'Andre Swift #32 of the Detroit Lions (Photo by Wesley Hitt/Getty Images)

The 49ers visit the Lions in Week 1 to open up the 2021 season, and it’ll be in the Niners’ best interest to ensure these three opponents don’t do damage.

A year ago, the San Francisco 49ers unfortunately let Arizona Cardinals star wide receiver DeAndre Hopkins go wild in a Week 1 regular-season opener that ultimately led to the Niners starting off their 2020 campaign with a 0-1 record.

This year, San Francisco will want to avoid the same kind of pitfall when it takes to the road for a Week 1 bout against the Detroit Lions.