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49ers mailbag: Panic over Garoppolo, fullback, long snapper?

SANTA CLARA — A 4-0 start isn’t enough to alleviate some 49ers’ fans concerns, so let’s try doing that in this week’s mailbag via questions through my Instagram and Twitter outreach program.

If Juice is a no-go for Sunday, what changes does Kyle make in the run game? (@geoffcast)

Fullback Kyle Juszczyk, arguably the MVP of the NFL’s No. 1 rushing attack, indeed is out for at least Sunday’s game at the Los Angeles Rams. He has a sprained medial collateral ligament in his left knee, requiring four to six weeks of rest and rehabilitation.